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4-Aminobenzoic acid

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1. STRUCTURE
4-Aminobenzoic acid
2. PRODUCT NAME & DETAILS
Product Name 4-Aminobenzoic acid
Product Code 001960
CAS No 150-13-0
HS Code 2916.31.90
Molecular Formula C7H7NO2
Molecular Wt. 137.13
3. REGULATORY INFORMATION
Chemical nameCommon names and synonymsCAS numberEC number
Pyridinium p-toluenesulfonatePyridinium toluene-4-sulphonate24057-28-124057-28-1
European Inventory of Existing Commercial Chemical Substances (EINECS)Listed
EC InventoryListed
United States Toxic Substances Control Act (TSCA) InventoryListed
China Catalog of Hazardous chemicals 2015Not Listed
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)Listed
Korea Existing Chemicals List (KECL)Listed
Canadian Domestic Substance List (DSL)Listed
Canadian Non-Domestic Substance List (NDSL)Not Listed
Japanese Existing and New Chemical Substances Inventory (ENCS)Listed


4. SPECIFICATION
Physical AppearanceWhite To Off White Powder
Melting Point184-189°C
Moisture Content (KF)NMT 0.5%
Solubility50 mg / ml ETOH, Faint Yellow Solution
Assay (by Titration Non Aqueous)98.5% to 100.5%
2-Aminobenzoic Acid (by TLCNMT 0.1%
3-Aminobenzoic Acid (by TLC)NMT 0.1%
5. APPLICATION- It is used as raw material to manufacture industrial organic chemicals.

- It is intermediate of Pheniramine, Bentiromide, Benzocaine, Benzonatate, Fadrozole, Methotrexate, Nafamostat, Procaine, Ramosetron, Tetracaine, Butylcaine, Camostat, Candoxatril, Candoxatrilat, Deanol Acetamidobenzoate, Padimate, Xemilofiban, Octenidene, Pinacidil, Cetaben, Octenidine, Pinacidil, Cetaben, Octylonium, Acedoben, Ciclometasone, Pemetrexed.

- 4-Aminobenzoic acid acts as a gastric acid secretion inhibitor. It is employed as an intermediate in the synthesis of folate (Vitamin BX), azo dyes and cross linking agents. It is also useful in biomedical sector for the preparation of local anesthetic and ointments. It is widely used in industries to make pharmaceutical products, flavors and preservatives. It is actively involved as a UV-blocking ingredient in sun tan cosmetics.

- 4-Aminobenzoic acid may be used in the following studies
  • Covalent modification of glassy carbon electrode.
  • Spectrophotometric determination of the trace amounts of dopamine, methyldopa and levodopa.
  • Synthesis of 1:1 proton-transfer compound with 5-sulfosalicylic acid.
- 4-Aminobenzoic acid (4-ABA) can be used in the synthesis of: 
  • Schiff bases based on 4-ABA with good antibacterial activity.
  • Co(II) and Mn(II) salts of 4-ABA supported on silica gel which in turn can be used as catalysts in oxidation of thiols to disulfides.
  • 4-amino-3-bromobenzoic acid.
  • Curing agent, N-(4-carboxyphenyl)trimellitimide (NCPT). 
6. HAZARD CLASSIFICATION
Non-Hazardous substance.
              Irritant
7. ANNUAL CAPACITY
5 MT.
8. STORAGE CONDITION
Store in closed container at ambient temperature. Avoid direct sun light
9. PACKING DETAILS

20 kg net  in corrugated box with two PE liners, strip sealed separately

10. SHELF LIFE
1 year.
Disclaimer
Typical properties should not be considered as specification.
Product covered by valid patents are not offered or supplied for commercial use. The Patent position should be verified by the customer.
Products will not be supplied to countries where they could be in conflict with existing patents.
Products currently covered by valid US patents are offered for R&D use in accordance with 35 USC 271 (e) (I) Above information is given in good faith and without warrenty.
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Frequently Asked Questions

Q1. What is 4-Aminobenzoic Acid (PABA) used for?

 A1. 4-Aminobenzoic Acid (PABA) is a white to off-white powder, also called PABA (assay 98.5–100.5%, melting point 184–189 °C) used as an intermediate for drugs such as benzocaine, procaine, tetracaine, methotrexate and pemetrexed, and for folate, azo dyes and cross-linking agents. It is also cited as a UV-blocking ingredient in sun care products.


Q2. What are the key specifications of 4-Aminobenzoic Acid (PABA)?

 A2. A white to off-white powder, also called PABA; assay 98.5–100.5%, melting point 184–189 °C. CAS 150-13-0.


Q3. How is 4-Aminobenzoic Acid (PABA) packed and how long is its shelf life?

 A3. It is supplied in 20 kg corrugated boxes with two strip-sealed PE liners. Shelf life is 1 year when stored in a closed container at ambient temperature, away from direct sunlight.


Q4. What is the annual capacity for 4-Aminobenzoic Acid (PABA)?

 A4. Sarex Fine Chemicals manufactures 4-Aminobenzoic Acid (PABA) in India with an annual capacity of 5 MT.