6-Nitro-7-chloro-4-hydroxy quinazoline

6-NITRO-7-CHLORO-4-HYDROXY QUINAZOLINE | Afatinib

1. STRUCTURE
6-Nitro-7-chloro-4-hydroxy quinazoline
2. PRODUCT NAME & DETAILS
Product Name 6-Nitro-7-chloro-4-hydroxy quinazoline
Product Code 002671
CAS No 53449-14-2
HS Code 2933.99.00
Molecular Formula C8H4CIN3O3
Molecular Wt. 225.590
3. SPECIFICATION
Physical Appearance
Pale Yellow Powder to Light Brown Powder
Melting Point
> 280 °C
Identification (HPLC)
RT of Sample Should Matches with Standard
Moisture Content (KF)
NMT 0.5%
7 Chloro-4[1h]-quinazolinone
MAX 0.5%
Any Others Impurity 5,7-Dichloro-4[1h]quinazollnone
MAX 0.1%
+7-chloro-8nitro-4[1 h]quinazolin One
MAX  1.5%
Assay (HPLC)
NLT 98%
4. APPLICATION It is use as intermediate of Afatinib and Afatinib Dimaleate.
It is use in Anti-Cancer, Oncology Drug.
5. HAZARD  CLASSIFICATION Hazardous Substance (UN No. 2811).

Acute-Toxic

Irritant

6. CAPACITY 2 MT Per Month.
7. STORAGE  CONDITION
Store in closed container at ambient temperature. Avoid direct sunlight.
8. PACKING DEATILS
Outer Packing : 25 kg HDPE UN Approved Open Mouth Drum  
Inner Packing : 2 plastic liner with strip seal individually on each liner
9. SHELF LIFE
1 year.
Disclaimer
Typical properties should not be considered as specification.
Product covered by valid patents are not offered or supplied for commercial use. The Patent position should be verified by the customer.
Products will not be supplied to countries where they could be in conflict with existing patents.
Products currently covered by valid US patents are offered for R&D use in accordance with 35 USC 271 (e) (I) Above information is given in good faith and without warrenty.

The above information is given in good faith and is without warranty